But some say Bowie’s creative vision mocks Christianity, and wish it was gone altogether.

“The video is offensive and distasteful. It is a misrepresentation of the multitudes of clergy who have given their lives to help hurting people. Undeniably, some clergy have misused their position, but to focus on these few is a character assault of their position and call,” Jay Lowder of Harvest Ministries told FOX411’s Pop Tarts column. “Bowie’s verse claiming ‘they work with Satan while they dress like saints,’ is to attribute God’s work through man as being sinister and evil in its origin. I find it hard to excavate any level of truth or reality from this video except Jesus was continually in the midst of those who were blind and sinful.”

And according to emerging songstress Erica Chase, music and art is the one place where boundaries can be pushed and rules can be broken.

“Artists have the ability to say what lay people and politicians often cannot because there is a demand for it,” she continued. “And religion encircles the great unknown: what is the purpose of this life and what happens after. Bowie and Gaga are just as uncertain as you and I about all that, so why can’t we enjoy a catchy song with an imaginative video to boot?”

A rep for Bowie did not respond to a request for further comment.